Miami Dolphins at Buffalo Bills Odds, Spread & Total – Sunday, Nov 22
Dolphins and Bills meet Sunday, Nov 22 at 1:00 PM ET at Highmark Stadium in Orchard Park. Bills is favored by 16.5 at DraftKings; the total is 46.5.
@
Highmark Stadium
Orchard Park, NY
CBS
Weather: Cloudy, light drizzle possible, 46°F
What to watch
- InjuriesListed out for the Dolphins: Aaron Brewer (C), Jared Wayne (WR) and 2 more; for the Bills: Tyrell Shavers (WR) and Spencer Brown (OT, doubtful).
- WeatherForecast near the start: Cloudy, light drizzle possible, 46°F, wind 21 mph (gusts 37 mph), 18% chance of rain.
Facts from the data on this page at the last refresh. Odds change; this is not a prediction or betting advice.
Odds across books
| Market | DraftKingsESPN (DraftKings) |
|---|---|
| MIA spread | +16.5 -110 |
| BUF spread | -16.5 -110 |
| MIA ML | +950 |
| BUF ML | -1650 |
| Over | O 46.5 -110 |
| Under | U 46.5 -110 |
Highlighted = best price among books legal in your state (with your state set). Odds change; confirm with the sportsbook. No Hard Rock Bet or FanDuel line for this game at the last pull.
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Line movement
Line movement · DraftKings
| Market | Open | Now | Move |
|---|---|---|---|
| Spread (BUF) | -16.5 | -16.5 | no change |
| Total | 46.5 | 46.5 | no change |
| BUF moneyline | -1800 | -1650 | +150 |
| MIA moneyline | +1000 | +950 | -50 |
Open = first line we recorded (Fri, Nov 13 · 12:15 AM ET). Spread shown from the BUF side.
Game-day weather
Cloudy, light drizzle possible · Orchard Park, New York
46°F (feels like 34°F), wind 21 mph W, gusts 37, 18% chance of rain.
Forecast at kickoff from Open-Meteo, as of Sat, Nov 14 · 1:15 PM ET.
Form & injuries
Records & recent form
| Team | Record | Home/Away | Last 10 | Streak | Last 5 |
|---|---|---|---|---|---|
| MIA | 1-7 | 1-3 | 1-7 | L2 | LLWLL |
| BUF | 7-1 | 3-1 | 7-1 | W4 | LWWWW |
MIA: 4th in AFC East · BUF: 1st in AFC East
Home/Away = MIA on the road, BUF at home.
Last five games
Dolphins
- L @ Minnesota Vikings 15-10
- L vs Cincinnati Bengals 31-24
- W @ New York Jets 28-25
- L vs New England Patriots 24-19
- L vs Detroit Lions 19-9
Bills
- L vs New England Patriots 29-26
- W @ Los Angeles Rams 37-34 OT
- W @ Las Vegas Raiders 33-30
- W vs Baltimore Ravens 36-10
- W @ Minnesota Vikings 23-6
Injuries
Dolphins
- Aaron Brewer C Out Concussion
- Jared Wayne WR Out Quadriceps
- Darrell Baker Jr. CB Out Knee
- Chris Bell WR Doubtful Knee
- Malik Willis QB Injured Reserve Abdomen
Bills
- Tyrell Shavers WR Out Knee - ACL
- Spencer Brown OT Doubtful Ankle
- Jordan Hancock CB Questionable Hamstring
- Christian Benford CB Questionable Wrist
- Sam Franklin Jr. S Questionable Shoulder
Source: ESPN injury reports at the last data refresh.
Team leaders
- Passing Yards Josh Allen 156/236, 2,027 YDS, 12 TD, 6 INT
- Rushing Yards James Cook III 169 CAR, 814 YDS, 8 TD
- Receiving Yards Dalton Kincaid 30 REC, 429 YDS, 2 TD
- Sacks Greg Rousseau 8
- Tackles Terrel Bernard 57
- Rushing Yards Ollie Gordon II 107 CAR, 463 YDS, 4 TD
- Receiving Yards Malik Washington 33 REC, 350 YDS, 1 TD
- Sacks Chop Robinson 4
Out, Doubtful and injured-reserve players are left off. Questionable and day-to-day players stay, marked with a badge.
Built from LineSmart data refreshed Sat, Nov 14, 2026 · 5:45 PM ET. Odds are for reference and may change; confirm with the sportsbook. For adults 21+.