Detroit Lions at Buffalo Bills: final score & closing odds

Detroit Lions

1-1

Final

Thu, Sep 17, 2026 · 8:15 PM ET

Highmark Stadium

Orchard Park, NY

Prime Video

Buffalo Bills

2-0

Final score

Final: Detroit Lions 31, Buffalo Bills 41. Closing lines not recorded.

Closing lines

Closing lines not recorded

Next games

Built from LineSmart data refreshed Sun, Nov 1, 2026 · 3:37 AM ET. Odds are for reference and may change; confirm with the sportsbook. For adults 21+.

Teams

More Lions at Bills

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Baltimore Ravens at Buffalo Bills Sun, Nov 1 · 1:00 PM ET
Minnesota Vikings at Detroit Lions Sun, Nov 1 · 1:00 PM ET
Green Bay Packers at Detroit Lions GB 17, DET 20
Buffalo Bills at Las Vegas Raiders BUF 33, LV 30
Buffalo Bills at Los Angeles Rams BUF 37, LAR 34 (OT)
Detroit Lions at Arizona Cardinals DET 45, ARI 21
Detroit Lions at Carolina Panthers DET 26, CAR 32
New England Patriots at Buffalo Bills NE 29, BUF 26