Arizona Cardinals at Kansas City Chiefs Odds, Spread & Total – Sunday, Nov 22
Cardinals and Chiefs meet Sunday, Nov 22 at 1:00 PM ET at Arrowhead Stadium in Kansas City. Chiefs is favored by 14 at DraftKings; the total is 42.5. At DraftKings, the spread has moved from Chiefs -11.5 to -14 and the total from 44.5 to 42.5.
@
Arrowhead Stadium
Kansas City, MO
CBS
Weather: Overcast, 52°F
What to watch
- Line moveChiefs spread moved from -11.5 to -14 and the total from 44.5 to 42.5 since the opening line (DraftKings).
- InjuriesListed out for the Cardinals: Jon Gaines II (G) and Hjalte Froholdt (C); for the Chiefs: Kenneth Walker III (RB), Jaylon Moore (OT) and 1 more.
- WeatherForecast near the start: Overcast, 52°F, wind 6 mph (gusts 16 mph).
Facts from the data on this page at the last refresh. Odds change; this is not a prediction or betting advice.
Odds across books
| Market | DraftKingsESPN (DraftKings) |
|---|---|
| ARI spread | +14 -110 |
| KC spread | -14 -110 |
| ARI ML | +625 |
| KC ML | -950 |
| Over | O 42.5 -105 |
| Under | U 42.5 -115 |
Highlighted = best price among books legal in your state (with your state set). Odds change; confirm with the sportsbook. No Hard Rock Bet or FanDuel line for this game at the last pull.
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Line movement
Line movement · DraftKings
| Market | Open | Now | Move |
|---|---|---|---|
| Spread (KC) | -11.5 | -14 | -2.5 |
| Total | 44.5 | 42.5 | -2 |
| KC moneyline | -600 | -950 | -350 |
| ARI moneyline | +440 | +625 | +185 |
- Spread moved 2.5 pts
- Total moved 2
Open = first line we recorded (Fri, Nov 13 · 12:15 AM ET). Spread shown from the KC side.
Game-day weather
Overcast · Kansas City, Missouri
52°F (feels like 47°F), wind 6 mph NNE, gusts 16, 7% chance of rain.
Forecast at kickoff from Open-Meteo, as of Sat, Nov 14 · 1:15 PM ET.
Form & injuries
Records & recent form
| Team | Record | Home/Away | Last 10 | Streak | Last 5 |
|---|---|---|---|---|---|
| ARI | 3-6 | 3-3 | 3-6 | L1 | LWLWL |
| KC | 6-2 | 4-0 | 6-2 | W1 | WWLLW |
ARI: 4th in NFC West · KC: 2nd in AFC West
Home/Away = ARI on the road, KC at home.
Last five games
Cardinals
- L vs Detroit Lions 45-21
- W @ Los Angeles Rams 18-16
- L vs Denver Broncos 30-16
- W @ Dallas Cowboys 33-30 OT
- L @ Seattle Seahawks 17-3
Chiefs
- W @ Las Vegas Raiders 30-27
- W vs Los Angeles Chargers 22-6
- L @ Seattle Seahawks 20-3
- L @ Denver Broncos 28-24
- W vs New York Jets 35-12
Injuries
Cardinals
- Jon Gaines II G Out Ankle
- Hjalte Froholdt C Out Concussion
- Hunter Long TE Questionable Knee
- Jayden Williams OT Questionable Knee
- Zachary Carter DT Injured Reserve Knee
Chiefs
- Kenneth Walker III RB Out Groin
- Jaylon Moore OT Out Ankle
- Peter Woods DT Out Neck
- Jaydn Ott RB Questionable Hamstring
- Mansoor Delane CB Questionable Shoulder
Source: ESPN injury reports at the last data refresh.
Team leaders
- Passing Yards Patrick Mahomes 177/263, 2,037 YDS, 14 TD, 4 INT
- Receiving Yards Travis Kelce 33 REC, 482 YDS, 2 TD
- Sacks George Karlaftis 4
- Tackles Nick Bolton 80
- Passing Yards Gardner Minshew II 38/53, 354 YDS, 3 TD
- Rushing Yards Tyler Allgeier 89 CAR, 369 YDS, 2 TD
- Receiving Yards Trey McBride 73 REC, 598 YDS, 5 TD
- Sacks Budda Baker 3.5
Out, Doubtful and injured-reserve players are left off. Questionable and day-to-day players stay, marked with a badge.
Built from LineSmart data refreshed Sat, Nov 14, 2026 · 5:45 PM ET. Odds are for reference and may change; confirm with the sportsbook. For adults 21+.