| Oklahoma Sooners at Michigan Wolverines | OU 10, MICH 17 | — | — | — |
| Arizona State Sun Devils at Texas A&M Aggies | ASU 20, TA&M 48 | — | — | — |
| Washington State Cougars at Kansas State Wildcats | WSU 7, KSU 34 | — | — | — |
| East Tennessee State Buccaneers at North Carolina Tar Heels | ETSU 3, UNC 35 | — | — | — |
| Old Dominion Monarchs at Virginia Tech Hokies | ODU 21, VT 44 | — | — | — |
| Wake Forest Demon Deacons at Purdue Boilermakers | WAKE 38, PUR 36 (2OT) | — | — | — |
| Howard Bison at Indiana Hoosiers | HOW 0, IU 55 | — | — | — |
| Penn State Nittany Lions at Temple Owls | PSU 27, TEM 9 | — | — | — |
| South Florida Bulls at Army Black Knights | USF 28, ARMY 24 | — | — | — |
| App State Mountaineers at East Carolina Pirates | APP 27, ECU 24 | — | — | — |
| Wofford Terriers at Kent State Golden Flashes | WOF 15, KENT 36 | — | — | — |
| Wagner Seahawks at James Madison Dukes | WAG 3, JMU 87 | — | — | — |
| Gardner-Webb Runnin' Bulldogs at Liberty Flames | GWEB 23, LIB 24 | — | — | — |
| Western Kentucky Hilltoppers at Georgia Bulldogs | WKU 20, UGA 70 | — | — | — |
| UT Martin Skyhawks at West Virginia Mountaineers | UTM 7, WVU 52 | — | — | — |
| Colgate Raiders at Central Michigan Chippewas | COLG 10, CMU 13 | — | — | — |
| Holy Cross Crusaders at Miami (OH) RedHawks | HC 7, M-OH 45 | — | — | — |
| Oregon Ducks at Oklahoma State Cowboys | ORE 31, OKST 39 | — | — | — |
| Stony Brook Seawolves at Ball State Cardinals | STBK 17, BALL 41 | — | — | — |
| Alabama Crimson Tide at Kentucky Wildcats | ALA 45, UK 17 | — | — | — |
| Mississippi State Bulldogs at Minnesota Golden Gophers | MSST 38, MINN 13 | — | — | — |
| Weber State Wildcats at Colorado Buffaloes | WEB 21, COLO 52 | — | — | — |
| UCF Knights at Pittsburgh Panthers | UCF 7, PITT 12 | — | — | — |
| Arizona Wildcats at BYU Cougars | ARIZ 17, BYU 28 | — | — | — |
| California Golden Bears at Syracuse Orange | CAL 21, SYR 18 | — | — | — |
| Duke Blue Devils at Illinois Fighting Illini | DUKE 31, ILL 27 | — | — | — |
| Eastern Michigan Eagles at Michigan State Spartans | EMU 7, MSU 35 | — | — | — |
| Maryland Terrapins at UConn Huskies | MD 38, CONN 14 | — | — | — |
| Utah State Aggies at Washington Huskies | USU 14, WASH 16 | — | — | — |
| Rice Owls at Notre Dame Fighting Irish | RICE 0, ND 52 | — | — | — |
| UTSA Roadrunners at Texas State Bobcats | UTSA 31, TXST 26 | — | — | — |
| UL Monroe Warhawks at UAB Blazers | ULM 20, UAB 26 | — | — | — |
| Robert Morris Colonials at Akron Zips | RMU 10, AKR 45 | — | — | — |
| Central Connecticut Blue Devils at Toledo Rockets | CCSU 10, TOL 63 | — | — | — |
| Sacred Heart Pioneers at Massachusetts Minutemen | SHU 10, MASS 37 | — | — | — |
| UNLV Rebels at North Texas Mean Green | UNLV 6, UNT 44 | — | — | — |
| UC Davis Aggies at SMU Mustangs | UCD 10, SMU 56 | — | — | — |
| Northern Colorado Bears at Wyoming Cowboys | UNCO 13, WYO 21 | — | — | — |
| Mercyhurst Lakers at New Mexico Lobos | MERC 7, UNM 70 | — | — | — |
| Alabama State Hornets at Troy Trojans | ALST 17, TROY 34 | — | — | — |
| Delaware Blue Hens at Vanderbilt Commodores | DEL 26, VAN 35 | — | — | — |
| Campbell Fighting Camels at Florida Gators | CAM 3, FLA 52 | — | — | — |
| Memphis Tigers at Boise State Broncos | MEM 20, BOIS 38 | — | — | — |
| Buffalo Bulls at Florida International Panthers | BUFF 20, FIU 33 | — | — | — |
| Jacksonville State Gamecocks at Ohio Bobcats | JXST 27, OHIO 29 (4OT) | — | — | — |
| Monmouth Hawks at Western Michigan Broncos | MONM 14, WMU 49 | — | — | — |
| Towson Tigers at South Carolina Gamecocks | TOW 9, SC 45 | — | — | — |
| Tennessee Volunteers at Georgia Tech Yellow Jackets | TENN 45, GT 24 | — | — | — |
| Western Carolina Catamounts at Cincinnati Bearcats | WCU 10, CIN 62 | — | — | — |
| Southern Jaguars at Houston Cougars | SOU 6, HOU 77 | — | — | — |
| Bowling Green Falcons at Nebraska Cornhuskers | BGSU 7, NEB 56 | — | — | — |
| Southern Utah Thunderbirds at Colorado State Rams | SUU 24, CSU 58 | — | — | — |
| Tulsa Golden Hurricane at Sam Houston Bearkats | TLSA 23, SHSU 17 | — | — | — |
| Illinois State Redbirds at Northern Illinois Huskies | ILST 28, NIU 24 | — | — | — |
| South Alabama Jaguars at Tulane Green Wave | USA 24, TULN 28 | — | — | — |
| West Georgia Wolves at Arkansas State Red Wolves | WES 7, ARST 52 | — | — | — |
| Georgia State Panthers at Kennesaw State Owls | GAST 31, KENN 17 | — | — | — |
| Middle Tennessee Blue Raiders at Marshall Thundering Herd | MTSU 26, MRSH 28 | — | — | — |
| Lindenwood Lions at Missouri State Bears | LIN 14, MOST 48 | — | — | — |
| San Diego State Aztecs at UCLA Bruins | SDSU 10, UCLA 28 | — | — | — |
| Western Illinois Leathernecks at Wisconsin Badgers | WIU 9, WIS 36 | — | — | — |
| Ohio State Buckeyes at Texas Longhorns | OSU 23, TEX 24 | — | — | — |
| Texas Tech Red Raiders at Oregon State Beavers | TTU 35, ORST 24 | — | — | — |
| Iowa State Cyclones at Iowa Hawkeyes | ISU 13, IOWA 16 | — | — | — |
| Navy Midshipmen at Florida Atlantic Owls | NAVY 30, FAU 38 | — | — | — |
| Louisiana Tech Bulldogs at LSU Tigers | LT 14, LSU 45 | — | — | — |
| Fordham Rams at Coastal Carolina Chanticleers | FOR 7, CCU 45 | — | — | — |
| Charlotte 49ers at Ole Miss Rebels | CLT 9, MISS 41 | — | — | — |
| Grambling Tigers at TCU Horned Frogs | GRAM 7, TCU 63 | — | — | — |
| Prairie View A&M Panthers at Baylor Bears | PV 3, BAY 44 | — | — | — |
| Southern Miss Golden Eagles at Auburn Tigers | USM 8, AUB 43 | — | — | — |
| Cal Poly Mustangs at San José State Spartans | CP 20, SJSU 30 | — | — | — |
| Texas Southern Tigers at UTEP Miners | TXSO 10, UTEP 51 | — | — | — |
| Georgia Southern Eagles at Clemson Tigers | GASO 7, CLEM 22 | — | — | — |
| North Dakota State Bison at Air Force Falcons | NDSU 38, AFA 32 | — | — | — |
| Arkansas Razorbacks at Utah Utes | ARK 10, UTAH 43 | — | — | — |
| Sacramento State Hornets at Fresno State Bulldogs | SAC 3, FRES 49 | — | — | — |
| Montana State Bobcats at Nevada Wolf Pack | MTST 20, NEV 7 | — | — | — |
| Louisiana Ragin' Cajuns at USC Trojans | UL 30, USC 49 | — | — | — |
| New Mexico State Aggies at Hawai'i Rainbow Warriors | NMSU 19, HAW 29 | — | — | — |
