Houston Astros at Cleveland Guardians: final score & closing odds

Houston Astros

9-16

Final

Tue, Apr 21, 2026 · 6:10 PM ET

Progressive Field

Cleveland, Ohio

MLB.TV, CLEGuardians.TV, Space City Home Network

Cleveland Guardians

14-11

Final score

Final: Houston Astros 5, Cleveland Guardians 8. Closing lines not recorded.

Closing lines

Closing lines not recorded

Built from LineSmart data refreshed Sun, Nov 1, 2026 · 3:15 AM ET. Odds are for reference and may change; confirm with the sportsbook. For adults 21+.

Teams

More Astros at Guardians

Cleveland Guardians at Tampa Bay Rays CLE 3, TB 7
Tampa Bay Rays at Cleveland Guardians TB 3, CLE 1
Tampa Bay Rays at Cleveland Guardians TB 7, CLE 3
Tampa Bay Rays at Cleveland Guardians Fri, Oct 16 · 8:00 PM ET
Tampa Bay Rays at Cleveland Guardians TB 2, CLE 3
Cleveland Guardians at Tampa Bay Rays CLE 1, TB 3
Cleveland Guardians at Tampa Bay Rays CLE 7, TB 3
Chicago White Sox at Cleveland Guardians CHW 0, CLE 2
Cleveland Guardians at Chicago White Sox CLE 9, CHW 5
Cleveland Guardians at Chicago White Sox CLE 9, CHW 3

Other MLB games on Apr 21

Cincinnati Reds at Tampa Bay Rays CIN 12, TB 6
Milwaukee Brewers at Detroit Tigers MIL 12, DET 4
St. Louis Cardinals at Miami Marlins STL 5, MIA 3
Atlanta Braves at Washington Nationals ATL 4, WSH 11
New York Yankees at Boston Red Sox NYY 4, BOS 0
Minnesota Twins at New York Mets MIN 5, NYM 3
Baltimore Orioles at Kansas City Royals BAL 5, KC 6
Philadelphia Phillies at Chicago Cubs PHI 4, CHC 7
Pittsburgh Pirates at Texas Rangers PIT 1, TEX 5
San Diego Padres at Colorado Rockies SD 1, COL 0